Full Text
The Full Text of this article is available as a PDF (700.4 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Abate C., Patel L., Rauscher F. J., 3rd, Curran T. Redox regulation of fos and jun DNA-binding activity in vitro. Science. 1990 Sep 7;249(4973):1157–1161. doi: 10.1126/science.2118682. [DOI] [PubMed] [Google Scholar]
- Beck L. S., Deguzman L., Lee W. P., Xu Y., McFatridge L. A., Gillett N. A., Amento E. P. Rapid publication. TGF-beta 1 induces bone closure of skull defects. J Bone Miner Res. 1991 Nov;6(11):1257–1265. doi: 10.1002/jbmr.5650061117. [DOI] [PubMed] [Google Scholar]
- Border W. A., Ruoslahti E. Transforming growth factor-beta in disease: the dark side of tissue repair. J Clin Invest. 1992 Jul;90(1):1–7. doi: 10.1172/JCI115821. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Butta A., MacLennan K., Flanders K. C., Sacks N. P., Smith I., McKinna A., Dowsett M., Wakefield L. M., Sporn M. B., Baum M. Induction of transforming growth factor beta 1 in human breast cancer in vivo following tamoxifen treatment. Cancer Res. 1992 Aug 1;52(15):4261–4264. [PubMed] [Google Scholar]
- Chalazonitis A., Kalberg J., Twardzik D. R., Morrison R. S., Kessler J. A. Transforming growth factor beta has neurotrophic actions on sensory neurons in vitro and is synergistic with nerve growth factor. Dev Biol. 1992 Jul;152(1):121–132. doi: 10.1016/0012-1606(92)90162-a. [DOI] [PubMed] [Google Scholar]
- Cheifetz S., Bellón T., Calés C., Vera S., Bernabeu C., Massagué J., Letarte M. Endoglin is a component of the transforming growth factor-beta receptor system in human endothelial cells. J Biol Chem. 1992 Sep 25;267(27):19027–19030. [PubMed] [Google Scholar]
- Daopin S., Piez K. A., Ogawa Y., Davies D. R. Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily. Science. 1992 Jul 17;257(5068):369–373. doi: 10.1126/science.1631557. [DOI] [PubMed] [Google Scholar]
- Falanga V., Qian S. W., Danielpour D., Katz M. H., Roberts A. B., Sporn M. B. Hypoxia upregulates the synthesis of TGF-beta 1 by human dermal fibroblasts. J Invest Dermatol. 1991 Oct;97(4):634–637. doi: 10.1111/1523-1747.ep12483126. [DOI] [PubMed] [Google Scholar]
- Flanders K. C., Lüdecke G., Engels S., Cissel D. S., Roberts A. B., Kondaiah P., Lafyatis R., Sporn M. B., Unsicker K. Localization and actions of transforming growth factor-beta s in the embryonic nervous system. Development. 1991 Sep;113(1):183–191. doi: 10.1242/dev.113.1.183. [DOI] [PubMed] [Google Scholar]
- Flaumenhaft R., Abe M., Mignatti P., Rifkin D. B. Basic fibroblast growth factor-induced activation of latent transforming growth factor beta in endothelial cells: regulation of plasminogen activator activity. J Cell Biol. 1992 Aug;118(4):901–909. doi: 10.1083/jcb.118.4.901. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Giannini G., Clementi E., Ceci R., Marziali G., Sorrentino V. Expression of a ryanodine receptor-Ca2+ channel that is regulated by TGF-beta. Science. 1992 Jul 3;257(5066):91–94. doi: 10.1126/science.1320290. [DOI] [PubMed] [Google Scholar]
- Glaser B. M., Michels R. G., Kuppermann B. D., Sjaarda R. N., Pena R. A. Transforming growth factor-beta 2 for the treatment of full-thickness macular holes. A prospective randomized study. Ophthalmology. 1992 Jul;99(7):1162–1173. doi: 10.1016/s0161-6420(92)31837-8. [DOI] [PubMed] [Google Scholar]
- Heine U. I., Burmester J. K., Flanders K. C., Danielpour D., Munoz E. F., Roberts A. B., Sporn M. B. Localization of transforming growth factor-beta 1 in mitochondria of murine heart and liver. Cell Regul. 1991 Jun;2(6):467–477. doi: 10.1091/mbc.2.6.467. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Johns L. D., Flanders K. C., Ranges G. E., Sriram S. Successful treatment of experimental allergic encephalomyelitis with transforming growth factor-beta 1. J Immunol. 1991 Sep 15;147(6):1792–1796. [PubMed] [Google Scholar]
- Kim S. J., Park K., Koeller D., Kim K. Y., Wakefield L. M., Sporn M. B., Roberts A. B. Post-transcriptional regulation of the human transforming growth factor-beta 1 gene. J Biol Chem. 1992 Jul 5;267(19):13702–13707. [PubMed] [Google Scholar]
- Kuruvilla A. P., Shah R., Hochwald G. M., Liggitt H. D., Palladino M. A., Thorbecke G. J. Protective effect of transforming growth factor beta 1 on experimental autoimmune diseases in mice. Proc Natl Acad Sci U S A. 1991 Apr 1;88(7):2918–2921. doi: 10.1073/pnas.88.7.2918. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lefer A. M. Mechanisms of the protective effects of transforming growth factor-beta in reperfusion injury. Biochem Pharmacol. 1991 Sep 12;42(7):1323–1327. doi: 10.1016/0006-2952(91)90441-7. [DOI] [PubMed] [Google Scholar]
- Lin H. Y., Wang X. F., Ng-Eaton E., Weinberg R. A., Lodish H. F. Expression cloning of the TGF-beta type II receptor, a functional transmembrane serine/threonine kinase. Cell. 1992 Feb 21;68(4):775–785. doi: 10.1016/0092-8674(92)90152-3. [DOI] [PubMed] [Google Scholar]
- Lindholm D., Castrén E., Kiefer R., Zafra F., Thoenen H. Transforming growth factor-beta 1 in the rat brain: increase after injury and inhibition of astrocyte proliferation. J Cell Biol. 1992 Apr;117(2):395–400. doi: 10.1083/jcb.117.2.395. [DOI] [PMC free article] [PubMed] [Google Scholar]
- López-Casillas F., Cheifetz S., Doody J., Andres J. L., Lane W. S., Massagué J. Structure and expression of the membrane proteoglycan betaglycan, a component of the TGF-beta receptor system. Cell. 1991 Nov 15;67(4):785–795. doi: 10.1016/0092-8674(91)90073-8. [DOI] [PubMed] [Google Scholar]
- Manning A. M., Williams A. C., Game S. M., Paraskeva C. Differential sensitivity of human colonic adenoma and carcinoma cells to transforming growth factor beta (TGF-beta): conversion of an adenoma cell line to a tumorigenic phenotype is accompanied by a reduced response to the inhibitory effects of TGF-beta. Oncogene. 1991 Aug;6(8):1471–1476. [PubMed] [Google Scholar]
- Miller A., Lider O., Roberts A. B., Sporn M. B., Weiner H. L. Suppressor T cells generated by oral tolerization to myelin basic protein suppress both in vitro and in vivo immune responses by the release of transforming growth factor beta after antigen-specific triggering. Proc Natl Acad Sci U S A. 1992 Jan 1;89(1):421–425. doi: 10.1073/pnas.89.1.421. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Missero C., Ramon y Cajal S., Dotto G. P. Escape from transforming growth factor beta control and oncogene cooperation in skin tumor development. Proc Natl Acad Sci U S A. 1991 Nov 1;88(21):9613–9617. doi: 10.1073/pnas.88.21.9613. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Moses H. L., Yang E. Y., Pietenpol J. A. TGF-beta stimulation and inhibition of cell proliferation: new mechanistic insights. Cell. 1990 Oct 19;63(2):245–247. doi: 10.1016/0092-8674(90)90155-8. [DOI] [PubMed] [Google Scholar]
- Nathan C., Sporn M. Cytokines in context. J Cell Biol. 1991 Jun;113(5):981–986. doi: 10.1083/jcb.113.5.981. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pietenpol J. A., Münger K., Howley P. M., Stein R. W., Moses H. L. Factor-binding element in the human c-myc promoter involved in transcriptional regulation by transforming growth factor beta 1 and by the retinoblastoma gene product. Proc Natl Acad Sci U S A. 1991 Nov 15;88(22):10227–10231. doi: 10.1073/pnas.88.22.10227. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Qian S. W., Burmester J. K., Merwin J. R., Madri J. A., Sporn M. B., Roberts A. B. Identification of a structural domain that distinguishes the actions of the type 1 and 2 isoforms of transforming growth factor beta on endothelial cells. Proc Natl Acad Sci U S A. 1992 Jul 15;89(14):6290–6294. doi: 10.1073/pnas.89.14.6290. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Qian S. W., Kondaiah P., Casscells W., Roberts A. B., Sporn M. B. A second messenger RNA species of transforming growth factor beta 1 in infarcted rat heart. Cell Regul. 1991 Mar;2(3):241–249. doi: 10.1091/mbc.2.3.241. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Racke M. K., Dhib-Jalbut S., Cannella B., Albert P. S., Raine C. S., McFarlin D. E. Prevention and treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-beta 1. J Immunol. 1991 May 1;146(9):3012–3017. [PubMed] [Google Scholar]
- Roberts A. B., Kim S. J., Sporn M. B. Is there a common pathway mediating growth inhibition by TGF-beta and the retinoblastoma gene product? Cancer Cells. 1991 Jan;3(1):19–21. [PubMed] [Google Scholar]
- Roberts A. B., Roche N. S., Winokur T. S., Burmester J. K., Sporn M. B. Role of transforming growth factor-beta in maintenance of function of cultured neonatal cardiac myocytes. Autocrine action and reversal of damaging effects of interleukin-1. J Clin Invest. 1992 Nov;90(5):2056–2062. doi: 10.1172/JCI116087. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Roberts A. B., Sporn M. B. Mechanistic interrelationships between two superfamilies: the steroid/retinoid receptors and transforming growth factor-beta. Cancer Surv. 1992;14:205–220. [PubMed] [Google Scholar]
- Roberts A. B., Vodovotz Y., Roche N. S., Sporn M. B., Nathan C. F. Role of nitric oxide in antagonistic effects of transforming growth factor-beta and interleukin-1 beta on the beating rate of cultured cardiac myocytes. Mol Endocrinol. 1992 Nov;6(11):1921–1930. doi: 10.1210/mend.6.11.1282674. [DOI] [PubMed] [Google Scholar]
- Schlunegger M. P., Grütter M. G. An unusual feature revealed by the crystal structure at 2.2 A resolution of human transforming growth factor-beta 2. Nature. 1992 Jul 30;358(6385):430–434. doi: 10.1038/358430a0. [DOI] [PubMed] [Google Scholar]
- Shull M. M., Ormsby I., Kier A. B., Pawlowski S., Diebold R. J., Yin M., Allen R., Sidman C., Proetzel G., Calvin D. Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. Nature. 1992 Oct 22;359(6397):693–699. doi: 10.1038/359693a0. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Unsicker K., Flanders K. C., Cissel D. S., Lafyatis R., Sporn M. B. Transforming growth factor beta isoforms in the adult rat central and peripheral nervous system. Neuroscience. 1991;44(3):613–625. doi: 10.1016/0306-4522(91)90082-y. [DOI] [PubMed] [Google Scholar]
- Wang X. F., Lin H. Y., Ng-Eaton E., Downward J., Lodish H. F., Weinberg R. A. Expression cloning and characterization of the TGF-beta type III receptor. Cell. 1991 Nov 15;67(4):797–805. doi: 10.1016/0092-8674(91)90074-9. [DOI] [PubMed] [Google Scholar]
- Wu S. P., Theodorescu D., Kerbel R. S., Willson J. K., Mulder K. M., Humphrey L. E., Brattain M. G. TGF-beta 1 is an autocrine-negative growth regulator of human colon carcinoma FET cells in vivo as revealed by transfection of an antisense expression vector. J Cell Biol. 1992 Jan;116(1):187–196. doi: 10.1083/jcb.116.1.187. [DOI] [PMC free article] [PubMed] [Google Scholar]