Skip to main content
. 2005 Jan 18;92(2):284–289. doi: 10.1038/sj.bjc.6602322

Table 5. Risk factors affecting the overall survival rate determined by univariate and multivariate analysis of p53, p53R2, and the clinical response (a) or pathological response (b) to CRT in 62 and 36 ESCC patients, respectively.

  P
Risk  
  Univariate Multivariate ratio 95% CI
(a)        
p53 (−) vs p53 (+) 0.0011 0.0215 2.688 1.157–6.250
p53R2 (−) vs p53R2 (+) 0.0057 0.0185 2.469 1.164–5.235
CR+PR vs NC+PD 0.0009 0.2864 1.576 0.683–3.636
         
(b)        
p53 (−) vs p53 (+) 0.0145 0.1462 2.188 0.709–10.101
p53R2 (−) vs p53R2 (+) 0.0399 0.3059 1.515 0.566–6.098
Grade 2, 3 vs Grade 1 0.0006 0.0466 4.176 1.025–26.824

p53(+)/(−)=p53 positive/negative expression; p53R2(+)/(−)=p53R2 positive/negative expression; CRT=chemoradiation therapy; CR=complete response; PR=partial response; NC=no change; PD=progressive disease.