Table 5.
Gaussian Evolutionary Method (GEM) search mechanisms and genetic operators
Genetic operator (see Materials and Methods) | Local | Global | Discrete | Continuous |
Rotamer mutation operator | no | yes | yes | no |
Decreasing-based Gaussian mutation | no | yes | no | yes |
Self-adaptive Gaussian mutation | yes | noa | no | yes |
Family competition | yes | no | yes | yes |
a Self-adaptive Gaussian mutation may be viewed as both a local and a global search operator.