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. 2008 Feb 29;82(3):696–711. doi: 10.1016/j.ajhg.2008.01.008

Figure 1.

Figure 1

Frontal-Cortex DNA-Methylation Differences

Volcano plots showing raw p values for differential DNA methylation versus fold change observed when the hypomethylated fraction of brain DNA from psychosis patients was compared to that from unaffected individuals by use of 12K CpG-island microarrays. Each spot (red and black) represents an array probe averaged across all individuals in a group, with red spots denoting probes with FDR < 5%. SZ indicates schizophrenia, BD indicates bipolar disorder, and PSY indicates combined psychosis group (SZ and BD).