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. Author manuscript; available in PMC: 2008 Jun 21.
Published in final edited form as: J Biol Chem. 2007 Jun 1;282(31):22376–22386. doi: 10.1074/jbc.M700088200

Figure 7. Anti-Aβ1–11 antibody inhibits Aβ42 fibrils and oligomer-mediated toxicity.

Figure 7

Mouse primary neurons were incubated with Aβ42 oligomers and Aβ42 fibrils, in the presence or absence of anti-Aβ1–11 antibody or mouse IgG to irrelevant antigen (1:5, antibody/peptide molar ratio). Control cells were treated with the vehicle, and cell viability was assayed in all cultures using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Data were collected in triplicate and was expressed as a percentage of control ± S.D.