Table 2. QPCR validation of the arrays.

Neurons harvested by LCM from the same male and female control subjects used in the arrays, were used to test actin-gamma, ASYN, and HSP90. The levels of these genes determined with QPCR were in good accordance with the array results. Cells captured from the control cases as well as male and female PD subjects were used to test three other targets: beta-catenin, and KLK6. QPCR confirmed the array data for KLK6 and beta-catenin. Beta catenin’s decrease in the PD cases as determined by PCR was not as dramatic as in the arrays.