. 2008 May 9;283(19):13087–13099. doi: 10.1074/jbc.M800533200

TABLE 3.

Hepatic gene expression in AdHSL- and AdATGL-infected ob/ob mice Hepatic mRNA levels were assessed by qPCR. Data, expressed as means ± S.D., were normalized to β-actin gene expression. Data derived from AdGFP-infected animals are expressed as 100%, and those of the other groups are expressed as a percentage of the AdGFP-infected controls. Comparisons were made against AdGFP-infected animals using Student's t test. L-Fabp is liver fatty acid-binding protein.

Pathway/gene	Female			Male
Pathway/gene	AdGFP	AdHSL	AdATGL	AdGFP	AdHSL
	%AdGFP	%AdGFP	%AdGFP	%AdGFP	%AdGFP
FA oxidation
AOX	100 ± 43	129 ± 46	101 ± 36	100 ± 43	179 ± 44^a
CPT1	100 ± 45	217 ± 202	125 ± 43	100 ± 42	204 ± 80^b
PPARα	100 ± 22	115 ± 8	95 ± 29	100 ± 8	141 ± 16^a
Mitochondrial bioenergetics/lipid metabolism
UCP2	100 ± 36	72 ± 14	95 ± 22	100 ± 54	44 ± 14
FA uptake and transport
CD36	100 ± 31	97 ± 25	75 ± 34	100 ± 21	121 ± 27
L-Fabp	100 ± 38	104 ± 36	120 ± 50	100 ± 3	92 ± 36
Lipid synthesis and storage
FAS	100 ± 58	135 ± 60	146 ± 77	100 ± 30	89 ± 46
SCD1	100 ± 66	125 ± 54	216 ± 207	100 ± 80	92 ± 33
SREBP1c	100 ± 24	88 ± 30	97 ± 55	100 ± 14	89 ± 46
ADRP	100 ± 35	87 ± 20	103 ± 44	100 ± 13	108 ± 30

p < 0.05

p = 0.06