Table 5. Joint and marginal odds ratios (pooled cases) for rs10490924 and rs1061170.
|
rs10490924 |
rs1061170 |
rs10490924
risk (adjusted for rs1061170) |
||
|---|---|---|---|---|
| TT |
TC |
CC |
||
| GG |
1 |
3.59 |
4.38 |
1 |
| GT |
5.72 |
13.66 |
36.52 |
5.24 (95% CI: 3.08, 8.91) |
| TT |
7.63 |
38.77 |
227.57 |
15.30 (95% CI: 5.75,40.73) |
| rs1061170 risk (adjusted for rs10490924) | 1 | 3.32 (95% CI: 1.87, 5.91) | 6.12 (95% CI: 2.92, 12.85) | |
Marginal odds ratios are calculated based on a logistic regression model by assuming an additive effect of two SNPs after a logit transformation on odds ratio.