. 2008 Jun 24;131(8):2094–2105. doi: 10.1093/brain/awn112

Table 1.

Demographic and drug details of PD Patients and controls

No	Sex	Age	Sw- En	HY Off	HY On	UPDRS Off	UPDRS On	Years (diagnosis)	L-dopa mg/d	L-dopa equivalent¹	Nart error	Predicted FullScale IQ	MM SE	Fluency		Medications (mg)
														P	Animals	A	C	R	E	Other
1	F	53	80	2	2	24	14	8.7	900	2200	6	123	30	20	28	100		21
2	M	61	70	4	2	53	17	15.4	2200	2585	5	124	30	24	24	300				T 300
3	M	78	80	4	3	50	30	13.5	700	512	29	104	25	13	20					O 120
4	F	65	100	2	2	12	7	5.0	250	1090	30	103	30	17	24			21		O 50, D 30
5	M	65	70	2.5	2.5	36	19	13.5	700	1196	36	98	27	22	25				800	S 10
6	F	50	90	2.5	2	34	15	9.5	300	1200	27	105	27	11	19	200		15
7	F	78	90	2	1	14	1	5.7	600	600	28	105	29	12	17
8	M	64	90	2	2	20	17	3.0	400	1290	5	124	30	19	28	100				P 2.1
9	M	69	80	2	2	29	18	4.8	400	1120	45	91	29	10	19		4			S 1.25
10	F	65	90	3	2.5	38	30	4.6	600	1560	32	101	27	6	20			24
11	M	59	80	2.5	2	36	29	5.7	500	1140	13	117	30	23	24	200	4
12	F	59	70	2.5	2	34	31	5.5	300	1260	12	118	30	31	35		6
13	M	68	80	2.5	2	32	20	9.0	250	915	33	100	28	9	11		4			S 5
14	M	66	80	2.5	2	33	25	6.9	800	1009	37	97	26	11	16	200	1		600
15	F	75	80	2.5	2	34	26	10.7	1200	1745	2	127	27	23	17	200		18	800
16	F	62	90	3	1	26	10	5.4	500	1020	42	93	29	21	12			18	600
17	M	62	100	2.5	2	30	19	5.2	800	1640	42	93	28	8	24	100				P 1
18^*	M	75	70	3	2	32	22	5.6	1300	1475	15	115	26	18	16			9
19^**	M	63	70	2.5	2	39	14	10.1	600	1680	12	118	29	12	24	200		24	800

Patients
11m	Mean	65.1	82.1	2.6	2.0	31.9	19.2	7.8	700.0	1328.3	23.7	108.2	28.3	16.3	21.2
8 f	SD	7.7	9.8	0.4	0.5	10.2	8.2	3.5	467.6	502.7	14.2	11.9	1.6	6.7	5.9

Controls
8 m	Mean	67.4									14	116	29.1	16.1	21.8
9 f	SD	6.1									7.2	6	0.8	4.6	5

¹Equivalent levodopa dose = [levodopa (× 1.2 if COMT inhibitor)(× 1.2 if 10 mg of S or × 1.1 if 5 mg of S)] + [P × 400] + [R × 40] + [C × 160] + [pergolide × 200] + [bromocriptine × 10] + [lisuride × 160]; all doses are in milligrams. [Williams Gray C. J Neurosci 2007 27 4832–38]. *arachnoid cyst, excluded from imaging analysis, SwEn = Schwab and England; H Y = Hoehn and Yahr; UDPRS = Unified Parkinson's Disease Rating Scale motor subscale III; MMSE = Folstein Mini-Mental State Examination; NART = national adult reading test estimate of premorbid IQ. **dyskinetic ‘on’, excluded from imaging analysis. Other drugs as mg/day are: A = amantadine; C = Cabergoline; R = Ropinirole; E = entacapone; T = tolcapone; S = selegiline; P = pramipexole; O = orphenadrine, D = domperidone.