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. 2008 Nov 28;9:104. doi: 10.1186/1471-2350-9-104

Table 2.

Allelic and genotypic frequency comparison between fetal and control groups.

C677T-MTHFR
Genotype-Allele 		Frequencies by date of birth
82–84 85–87 88–90
Fetal Group (n = 110) (n = 129) (n = 105)
% n % n % n
CC 0.073** 8 0.008** 1 0.019** 2
CT 0.727** 80 0.705** 91 0.6*# 63
TT 0.2 22 0.287 37 0.381## 40
C allele 0.436** 96 0.36** 93 0.319**# 67
T allele 0.564** 124 0.64** 165 0.681**# 143
Control Group (n = 88) (n = 93) (n = 95)
% n % n % n
CC 0.33 29 0.301 28 0.305 29
CT 0.477 42 0.452 42 0.421 40
TT 0.193 17 0.247 23 0.274 26
C allele 0.568 100 0.527 98 0.516 98
T allele 0.432 76 0.473 88 0.484 92

Note: *p < 0.05; **p < 0.01 (significant values relative to controls). #p < 0.05; ##p < 0.01 (significant values relative to the 1982–1984 period)