TABLE 1.
Characteristics of Enterobacteriaceae strains exhibiting in vitro carbapenem nonsusceptibility and/or harboring the blaKPC gene
Source patient | Organism | Disk diffusion test result for antibiotica:
|
blaKPC genotype | |||||
---|---|---|---|---|---|---|---|---|
Carbapenem
|
Noncarbapenem
|
|||||||
Ertapenem | Imipenem | Meropenem | Cefepime | Ciprofloxacin | Gentamicin | |||
1 | K. pneumoniae | R | R | R | R | R | S | + |
K. pneumoniae | R | S | R | − | ||||
2 | E. cloacaeb | R | R | R | R | S | S | + |
E. cloacae | R | S | S | − | ||||
3 | P. mirabilis | I | R | S | S | S | S | + |
E. coli | R | S | S | − | ||||
Citrobacter freundii | I | S | S | − |
S, susceptible; I, intermediate; R, resistant. In additional susceptibility testing, the K. pneumoniae isolate recovered from patient 1 was intermediately susceptible to tigecycline and susceptible to colistin. Also, the E. cloacae isolate from patient 2 was intermediately susceptible to tigecycline and susceptible to colistin.
Recovered from a patient with polymicrobial Enterobacteriaceae bacteremia.