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. Author manuscript; available in PMC: 2009 Jan 13.
Published in final edited form as: Immunity. 2008 Jul;29(1):68–78. doi: 10.1016/j.immuni.2008.05.008

Figure 2. IFNAR expression by DC alters the balance between the Th17 and Th1 response.

Figure 2

2D2 T cells were incubated with BM-derived DC and 1 μg/ml of OT-2 peptide in cultures skewed to Th17 [rIL-6 and rTGFβ (A)] or Th1 [rIL-12 and IL-4 Ab (B)]. Supernatants harvested 24h after re-stimulation with soluble CD3 Ab were analyzed by ELISA in triplicate wells shown as mean ± SEM; representative of 5 and 3 experiments for (A) and (B), respectively.