. Author manuscript; available in PMC: 2009 Jan 28.

Published in final edited form as: Neuroreport. 2007 Nov 19;18(17):1761–1764. doi: 10.1097/WNR.0b013e3282f13e7a

Table 1.

SORL1 SNP information in the original study and in the TGEN dataset.

SNP order	dbSNP rs Number	Physical Map Location (bp)	Distance (bp) from Previous Marker	SNP Type	Orig order	TGEN order	NE FAD	Israeli Arab	TGEN
1	rs4935774	120,826,964		Upstream of 5′ UTR	1	T.1	0.20	0.18	0.39
2	rs578506	120,828,687	1,723	intron	2		0.07	ND
3	rs582446	120,833,069	4,382	intron	3		0.32	0.08
4	rs661057	120,834,164	1,095	intron	4		0.12	0.07
5	rs676160	120,845,443	11,279	intron		T.2			0.49
6	rs11218304	120,854,321	8,878	intron	5		0.27	0.046
7	rs676759	120,864,475	10,154	intron		T.3			0.57
8	rs560573	120,866,094	1,619	intron	6	T.4	0.64	0.29	0.55
9	rs985421	120,867,526	1,432	intron		T.5			0.28
10	rs593769	120,869,213	1,687	intron		T.6			0.57
11	rs12364988	120,872,836	3,623	H269H	7	T.7	0.15	0.041	0.33
12	rs668387	120,873,131	295	intron	8	T.8	0.52	0.021	0.32
13	rs689021	120,876,330	3,199	intron	9		0.71	0.040
14	rs641120	120,886,175	9,845	intron	10		0.57	0.07
15	rs11218313	120,888,081	1,906	intron		T.9			0.83
16	rs4935775	120,894,712	6,631	intron	11		0.22	0.030
17	rs12285364	120,898,436	3,724	intron	12		0.014	0.56
18	rs2298813	120,898,894	458	T528A	13		0.012	0.43
19	rs11600231	120,911,918	13,024	intron	14		0.69	0.12
20	rs2276346	120,919,686	7,768	intron	15	T.10	0.61	0.36	0.25
21	rs10502262	120,920,522	836	intron		T.11			0.17
22	SORL1-T833T	120,931,165	10,643	T833T	16		0.41	0.0026
23	rs556349	120,931,417	252	intron	17		0.0057	0.20
24	rs7131432	120,932,080	663	intron		T.12			0.14
25	rs11218340	120,936,564	4,484	intron	18		0.08	0.14
26	rs10892756	120,939,766	3,202	intron		T.13			0.49
27	rs11218346	120,944,391	4,625	intron		T.14			0.48
28	rs1790213	120,947,399	3,008	intron		T.15			0.33
29	rs11218347	120,951,758	4,359	intron		T.16			0.78
30	rs2070045	120,953,300	1,542	S1187S	19		0.031	0.00082
31	rs3824966	120,953,393	93	intron	20		0.15	0.15
32	rs1699103	120,957,136	3,743	intron		T.17			0.045
33	rs7116734	120,957,150	14	intron		T.18			0.30
34	rs11218350	120,957,861	711	intron		T.19			0.040
35	SORL1-18ex26	120,959,359	1,498	(−18) 5′ of exon 26	21		0.41	0.0091
36	rs1699102	120,962,172	2,813	N1246N	22		0.06	0.91
37	rs10892759	120,969,298	7,126	intron		T.20			0.021
38	rs1792113	120,970,156	858	intron		T.21			0.20
39	rs11218360	120,978,601	8,445	intron		T.22			0.42
40	rs7128608	120,978,808	207	intron		T.23			0.44
41	rs3824968	120,981,132	2,324	A1584A	23		0.0031	0.00073
42	rs1629493	120,982,306	1,174	intron		T.24			0.09
43	rs2282649	120,984,168	1,862	intron	24	T.25	0.020	0.64	0.26
44	rs726601	120,986,617	2,449	intron		T.26			0.07
45	rs1784931	120,988,148	1,531	intron		T.27			0.049
46	rs1010159	120,988,611	463	intron	25	T.28	0.09	0.91	0.14
47	rs1784933	120,994,626	6,015	intron	26		0.07	0.80
48	rs1614735	120,998,211	3,585	intron	27	T.29	0.010	0.96	0.19
49	rs17125558	120,999,237	1,026	intron		T.30			0.70
50	rs10892761	121,003,094	3,857	intron		T.31			0.56
51	rs1133174	121,006,965	3,871	downstream of 3′UTR	28		0.07	0.09
52	rs1131497	121,007,955	990	downstream of 3′UTR	29		0.20	0.06

Notes: The nominal P values for allelic association with AD are shown for each dataset. NE FAD -- north European familial AD dataset; Israeli-Arab -- Israeli-Arab case-control dataset, and TGEN – TGEN dataset. Boldface rs number indicates that the SNP was genotyped in both Rogaeva et al. [1] and Reiman et al. [4] studies. Bold face p-value indicates that the SNP is nominally associated with AD in the original study. Bold face p-value with white font, black background refer to significant results from analyses of the TGEN data.