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. 2006 Oct;32(Suppl 1):S44–S63. doi: 10.1093/schbul/sbl029

Table 3.

Theory of Mind (ToM) or Attributional Style (AS) and Functional Outcome (FO) in Schizophrenia (S)

Study Participants SC Measures FO Measures Major Findings
Pollice et al76 44 S or SA outpatients
MA = 33
Male: 77.3%
Yrs Ed: 11.6
Yrs Ill: 10.6
Clor eq: 289
First-order ToM from Sally and Anne and Cigarettes tasks; second-order ToM from Ice Cream Van and Burglar tasks; also combined measures for global ToM score Community function—Disability Assessment Schedule: Self-care, social contact, work activity, global rating of community functioning made by interviewer • Global community functioning correlated with combined ToM (r = .43, P < .01) and second-order ToM (r = .30, P < .05) but not first-order ToM (r = .276); effects remained or were strengthened after partialling out IQ; second-order ToM explained 15% of the variance in global community functioning in stepwise regression
• Poor self-care and combined ToM significantly correlated after partialling out IQ (r = −.367, P < .05) but not before (r = −.002); not related to second-order (r = −.216) or first-order ToM (r = −.017)
• ToM not related to poor social contact (first order, r = −.078; second order, r = −.148; combined, r = −.201)
• ToM not associated with work ability (first order, r = −.026; second order, r = −.085; combined, r = −.020)
• 41.7% of effects were minimal to large range, 33.3% were small to moderate range, and 25% were moderate to large range
• Power for effect size of r = .3 is 0.501
Schenkel et al77 42 S or SA inpatients
MA = 41
Male: 60%
Yrs Ed: 12.1
Yrs Ill: ?
Clor eq: ?
Hinting Task Premorbid social functioning coded from charts • Group differences on ToM between poor and good premorbid social functioning groups (t(40) = 3.86, P < .0001)
• This is equivalent to a large effect size (r = .52)
• Power for effect size of r = .3 is 0.481
Lysaker et al51 40 S or SA outpatients
MA = 46
Male: 97.5%
Yrs Ed: 12.5
Yrs Ill: ∼21.4
Clor eq: ?
ASQ Community function—QLS: interpersonal function, community participation • Making a greater number of stable attributions predicted 8% of the variance in interpersonal function, 16% in community participation
• When cognitive variables were covaried, the relationships with the ASQ were the same except for community participation (NS)
• Effect sizes were small to moderate range and moderate to large range, respectively
• Power for effect size of r = .3 is 0.461
Waldheter et al52 29 S or SA inpatients
MA = 33
Male: 86%
Yrs Ed: 10.6
Yrs Ill: ?
Clor eq: 698–895
AIAQ
IPSAQ
Social behavior in milieu: Modified Overt Aggression Scale • Frequency of violence correlated with AIAQ hostility bias in accidental situations (r = .407, P < .05) but not in intentional (r = −.010) or ambiguous (r = .053) situations
• Severity of violence was not significantly correlated with any AIAQ hostility bias (accidental r = .368, intentional r = .129, ambiguous r = .106)
• The IPSAQ personalizing bias was correlated with severity (r = .325, P < .05) but not history (r = .269) of violence
• AIAQ hostility bias for ambiguous situations and the IPSAQ personalizing bias together predicted 4% of the variance in severity of violence
• 25% of effect sizes were minimal to small range, 37.5% were small to moderate range, and 37.5% were moderate to large range
• Power for effect size of r = .3 is 0.343

Note: SC = Social Cognition; NC = Neurocognition; SA = Schizoaffective; MA = Mean Age; NS = Not Significant; Yrs Ed = Years of Education; Yrs Ill = Number of Years Ill; Clor eq = Chlorpromazine equivalent (mg/d); AIAQ = Ambiguous Intentions Attributions Questionnaire (Combs et al, in preparation); ASQ = Attributional Style Questionnaire118; Burglar Task119; Cigarettes Task120; Disability Assessment Schedule (WHO)121; Hinting Task50; Ice Cream Van Task122; IPSAQ = Internal, Personal, and Situational Attributions Questionnaire123; Modified Overt Aggression Scale124; Sally and Anne Task125; QLS = Quality of Life Scale.56