Figure 6. Knockdown of BDNF partially attenuates the ability of the Npas4-minigene to elevate GABAergic synapses.
a, Cumulative distributions (left) and mean ± s.e.m. (right) of mIPSC inter-event intervals in neurons transfected with BDNF-RNAi (4086.1 ±140.7 ms) or BDNF-RNAi 1Npas4-minigene (3257.9 ± 117.7 ms). b, Cumulative distributions (left) and mean ± s.e.m. (30.1 ± 0.9 and 27.1 ± 0.7 pA, BDNF-RNAi versus BDNF-RNAi 1Npas4-minigene, right) of mIPSC amplitudes. Total numbers of neurons analysed in each condition (n) are indicated. ***P < 0.001.