Table 1.
Characteristics of subject groups
| Subjects with TS | Subjects without TS | |
|---|---|---|
| N | 33 | 42 |
| Male/Female | 25/8 | 24/18 |
| Average age (range) | 12.70 (9.92 to 15.83) | 12.69 (10.42 to 15.75) |
| Average movement mm rms (range) | 0.768 (0.19 to 1.56) | 0.731 (0.235 to 1.51) |
| Average IQ (range) | 105.4 (80 to 137) | 108.5 (86 to 137) |
| Average COWA-FAS z-score (range) | −0.32 (−3.9 to +3.2) | −0.02 (−2.7 to +2.3) |
| Average stroop interference z-score (range) | 0.15 (−0.9 to +2.2) | 0.26 (−0.9 to +1.8) |
| Average trails B z-score (range)* | 0.26 (−3.5 to +1.6) | 0.70 (−0.9 to +2.5) |
| Average tic severity rating (range)* | 16.3 (4 to 28) | 0 (0) |
| Average ADHD rating (range)* | 31.8 (4 to 76) | 10.1 (0 to 28) |
| Average OCD rating (range)* | 4.6 (0 to 18) | 0.1 (0 to 2) |
| No. on medications | 22 | 0 |
| No. with diagnosed co-morbidities | 17 | 0 |
Subjects with TS were used in both the COI and the direct comparison analyses, while the unaffected adolescent group was used in the direct comparison analysis (see text). The average Tic Severity rating was evaluated using only the motor tic and vocal tic sections of the YGTSS (maximum 50 points) and not the global assessment. Movement refers to in-scanner movement measured in millimeters (mm) of rms-variance. Significant differences (P < 0.05) by two-tailed t-test between the adolescent groups are indicated with an asterisk.