TABLE 1.
Biometrical parameters of wild-type and Fxr–/– mice
Male wild-type and Fxr–/– mice were fasted for 9 h. Body weight and blood glucose concentrations were determined before and after fasting. The values are averages ± S.E.; n = 12 (wild-types) and n = 10 (Fxr–/–).
| Wild-type mice | Fxr-/- mice | |
|---|---|---|
| Fed body weight (g) | 32.8 ± 1.0 | 33.9 ± 1.0 |
| Fasted body weight (g) | 29.9 ± 0.9 | 30.1 ± 0.9 |
| Weight loss (g) | 2.9 ± 0.1 | 3.8 ± 0.1a |
| Weight loss (%) | 8.8 ± 0.3 | 11.2 ± 0.9a |
| Fed blood glucose (mmol·l-1) | 9.5 ± 0.6 | 6.3 ± 0.3a |
| Fasted blood glucose (mmol·l-1) | 6.4 ± 0.6 | 5.1 ± 0.5a |
a
p < 0.05.