Table 1.
Description of the Four GWA Data Sets on Crohn Disease
GWA Data Set | Number of Cases/Controls | Ethnicity | Array Platform | IL12/IL23 Pathway Z Score | IL12/IL23 Pathway p Value |
---|---|---|---|---|---|
WTCCC | 1748/1480 | European ancestry | Affymetrix Mapping 500K | 3.8 | 0.00008 |
Ped-IBD | 647/4250 | European ancestry | Illumina HumanHap550 | 2.2 | 0.013 |
CDCC | 1083/2507 | European ancestry | Illumina HumanHap550 | 3.3 | 0.0004 |
CHOP-CD-AA | 40/527 | African Americans | Illumina HumanHap550 | 1.8 | 0.03 |