Table 3.
Second order reaction rate of MTSES of three cysteine mutants (m−1 s−1)
Control |
3-APMPA |
GABA |
||||
---|---|---|---|---|---|---|
Receptor | k2 | n | k2 | n | k2 | n |
L216C | 3381 ± 98 | 4 | 1802 ± 712 | 4 | 1480 ± 374* | 3 |
K217C | 11424 ± 696 | 4 | 9778 ± 489 | 3 | 3725 ± 1101** | 3 |
T218C | 545 ± 31 | 3 | 985 ± 130 | 4 | 850 ± 121 | 3 |
P < 0.05;
P < 0.01 (compared to control).