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. Author manuscript; available in PMC: 2009 Jun 15.
Published in final edited form as: Neurosignals. 2007 Dec 5;16(1):19–23. doi: 10.1159/000109755

Fig. 1.

Fig. 1

Hypothetical timeline for the onset and progression of sporadic as well as familial AD neurodegeneration and dementia. The green-, blue- and magenta-shaded bars indicate the time points at which preventative, disease-modifying and symptomatic interventions are likely to be most effective. From Shaw et al. [10], permission requested.