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. 2009 Jul 6;339:b2477. doi: 10.1136/bmj.b2477

Table 4.

 Other disabling comorbidities according to severity of age related changes in white matter (Fazekas scale) (633 patients with follow-up assessment*). Figures are numbers (percentages) of participants

Mild (n=282) Moderate (n=196) Severe (n=155) Total (n=633) P value
Depression 78 (27.7) 58 (29.6) 39 (25.2) 175 (27.6) 0.668
Falls in the last year 63 (22.3) 61 (31.3) 57 (36.8) 181 (28.6) 0.001
Osteoarthritis 82 (29.2) 56 (28.7) 39 (25.3) 177 (28.1) 0.421
Chronic obstructive pulmonary disease 27 (9.6) 18 (9.2) 20 (12.9) 65 (10.3) 0.326
Complaint of gait disturbances 100 (35.8) 74 (38.1) 83 (54.6) 257 (41.1) <0.001
Urinary disturbances 110 (39.0) 68 (34.7) 75 (48.4) 253 (40.0) 0.113
Visual impairment 37 (13.1) 35 (17.9) 39 (25.2) 111 (17.5) 0.002
Hearing loss 124 (44.0) 89 (45.4) 73 (47.1) 286 (45.2) 0.528

*Data missing for falls in past year (1), osteoarthritis (3), chronic obstructive pulmonary disease (1), complaint of gait disturbances (8).