Table 6.
Rate (95% confidence interval) per 100 person years at risk of transition to disability or death according to reason for referral and severity of age related changes in white matter
| Reasons for referral | Mild | Moderate | Severe | Total |
|---|---|---|---|---|
| Mild memory or motor problems, mood alterations | 15.8 (10.5 to 21.0) | 21.6 (14.3 to 28.8) | 38.1 (25.3 to 50.9) | 22.0 (17.7 to 26.2) |
| Minor cerebrovascular events | 7.2 (1.4 to 12.9) | 13.4 (6.6 to 20.2) | 32.4 (20.8 to 43.9) | 17.7 (12.8 to 22.6) |
| Incidental computed tomography/MRI finding | 7.0 (2.8 to 11.1) | 11.3 (3.5 to 19.2 | 28.2 (12.9 to 43.6) | 11.7 (7.6 to 15.7) |
| Other neurological symptoms | 10.2 (5.0 to 15.3) | 10.9 (4.7 to 17.0) | 19.8 (9.0 to 30.5) | 12.4 (8.5 to 16.2) |
| Other study controls, volunteers | 8.4 (3.4 to 13.4) | 11.7 (0 to 24.9) | 11.6 (0 to 27.7) | 9.2 (4.7 to 13.7) |
MRI=magnetic resonance imaging.