Table 3.
Bins achieving nominally significant evidence for linkage (European studies)
Pos | Bin | cM | Mb | PSR | POR |
---|---|---|---|---|---|
1 | 8.2* | 28.1-56.2 | 15.7-32.7 | 0.00057 | 0.06659 |
2 | 2.8 | 205.7-235.1 | 206.3-228.3 | 0.01016 | 0.35077 |
3 | 5.6* | 148.9-178.7 | 141.8-167.7 | 0.01718 | 0.33717 |
4 | 16.2* | 33.3-66.7 | 13.2-51.5 | 0.01775 | 0.15808 |
5 | 3.4 | 95.9-127.9 | 71.6-120.2 | 0.04359 | 0.62724 |
6 | 6.3* | 56.0-84.0 | 33.9-56.6 | 0.04433 | 0.44626 |
Shown are bins with nominally significant evidence for linkage (PSR < 0.05), in 22 samples or subsamples of European-ancestry families (see Table 1); the bolded p-value met empirical criteria for suggestive evidence for linkage (PSR < 0.0078). The results here did not meet aggregate criteria for significant genome-wide evidence for linkage in this subset of the data (10 bins with nominal PSR < 0.0475). See legend for Table 2 for additional details.