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. Author manuscript; available in PMC: 2009 Jul 31.
Published in final edited form as: Acta Neuropathol. 2008 Apr 30;116(1):17–24. doi: 10.1007/s00401-008-0383-1

Fig.2.

Fig.2

ImmunoEM showing double labeling of tau (PHF 1, 18 nm gold particles) and α-synuclein (NACP, 5 nm gold particles) epitopes. A neuron with lipofuscin (Lf), peripherally placed nucleus (N) and a cytoplasmic inclusion composed of electron dense granular material and filaments (*) (inset; Bar = 2 µm). Higher magnification of the boxed area of the inclusion shows the junction between tau filaments (arrows) and α-synuclein-labeled granule-coated filaments (double arrows). Bar = 0.15 µm