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. Author manuscript; available in PMC: 2009 Aug 21.
Published in final edited form as: Neurology. 2004 Feb 24;62(4):591–600. doi: 10.1212/01.wnl.0000110315.26026.ef

Table 6.

Correlation between Change in MRI and Change in Cognitive Test Performance among Normal Subjects

Hippocampus Entorhinal Cortex Whole Brain Ventricle
MMSE 0.14 (0.35) −0.02 (0.91) 0.37 (0.01)* −0.31 (0.04)*
DRS 0.24 (0.10) 0.14 (0.33) 0.46 (<0.00)* −0.49 (<0.00)*
AVLT 0.29 (0.05) 0.08 (0.60) 0.37 (0.01)* −0.49 (<0.00)*
LM II (%) 0.10 (0.51) 0.04 (0.79) 0.22 (0.16) −0.26 (0.10)

Values in table represent the Spearman correlation coefficients (p-value) between the annualized change in cognitive test score and annualized percent change in MRI measurement.

*

p < 0.05

Tests are MMSE = Mini Mental State Exam; DRS = Dementia Rating Scale; AVLT = Auditory Verbal Learning Test – delayed recall; LM II (%) = percent retention on Logical Memory subtest of the Wechsler Memory Scale –Revised.