. Author manuscript; available in PMC: 2009 Aug 31.

Published in final edited form as: Mol Psychiatry. 2008 Dec 30;14(4):376–380. doi: 10.1038/mp.2008.144

Table 2.

Singletons Burden Test Between Cases with Mania Onset ≤ 18 yr and Controls, and Between Earlier Onset and Later Onset Cases

Type of CNV	Tested	Cases	Controls	p-value
All	RATE	0.426	0.380	0.145
	PROP	0.343	0.290	0.039
Deletion	RATE	0.203	0.134	0.004
	PROP	0.189	0.123	0.001
Duplication	RATE	0.223	0.246	0.753
	PROP	0.192	0.191	0.498
		Younger onset patients	Older onset patients
Deletion	RATE	0.203	0.161	0.075
	PROP	0.189	0.147	0.050

The proportion of cases with at least one singleton CNV was nominally higher than controls (0.324 vs 0.290, P-value=0.054