. Author manuscript; available in PMC: 2010 Apr 1.

Published in final edited form as: Eur Respir J. 2009 Apr;33(4):793–796. doi: 10.1183/09031936.00150708

Table 3.

Unadjusted and adjusted mean increases in plasma KL-6 level in subjects with obstructive sleep apnea compared to controls

Model	Mean increase in plasma KL-6 in OSA compared to controls	95% CI	p value
Unadjusted	137	25 – 245	0.03
Adjusted for:
Age	136	24 – 248	0.03
Gender	139	27 – 251	0.03
Body mass index	133	17 – 149	0.04
ODI4	153	25 – 280	0.03
SpO₂ nadir	42	−95 – 179	0.56
Time SpO₂ < 90%	115	−8 – 239	0.08
Epworth sleepiness scale score	137	23 – 251	0.03
Brachial artery flow-mediated dilation	75	−92 – 242	0.39

ODI4 = Number of arterial oxyhemoglobin desaturation events ≥ 4% per hour of sleep;

SpO₂ = oxyhemoglobin saturation.

Each mean increase in plasma KL-6 is adjusted for the covariate in the first column