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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Genet Epidemiol. 2009 Apr;33(3):217–227. doi: 10.1002/gepi.20372

Table 3.

False-positive rate estimates of association tests for the mixture of the continuous and binary traits with the use of EGEE-based bivariate analyses and univariate analyses across various simulation scenarios under the significance level α = 0.05.

Sample Size N Allele Frequency q Correlation
Coefficient r
Analytical Methoda
B_EGEE U_b U_e
150 0.05 0.45 0.041 0.045 0.050
0.15 0.041 0.047 0.048
0 0.041 0.047 0.047
-0.15 0.044 0.047 0.048
-0.45 0.042 0.046 0.052
0.15 0.45 0.047 0.047 0.053
0.15 0.047 0.048 0.048
0 0.051 0.050 0.050
-0.15 0.048 0.050 0.050
-0.45 0.050 0.051 0.053
300 0.05 0.45 0.044 0.050 0.055
0.15 0.046 0.045 0.053
0 0.044 0.052 0.052
-0.15 0.046 0.046 0.053
-0.45 0.046 0.045 0.057
0.15 0.45 0.049 0.047 0.051
0.15 0.049 0.050 0.052
0 0.051 0.050 0.050
-0.15 0.049 0.051 0.051
-0.45 0.047 0.049 0.052
Note

—See note to Table 1 for definition of a.