Table 3.
False-positive rate estimates of association tests for the mixture of the continuous and binary traits with the use of EGEE-based bivariate analyses and univariate analyses across various simulation scenarios under the significance level α = 0.05.
Sample Size N | Allele Frequency q | Correlation Coefficient r |
Analytical Methoda |
||
---|---|---|---|---|---|
B_EGEE | U_b | U_e | |||
150 | 0.05 | 0.45 | 0.041 | 0.045 | 0.050 |
0.15 | 0.041 | 0.047 | 0.048 | ||
0 | 0.041 | 0.047 | 0.047 | ||
-0.15 | 0.044 | 0.047 | 0.048 | ||
-0.45 | 0.042 | 0.046 | 0.052 | ||
0.15 | 0.45 | 0.047 | 0.047 | 0.053 | |
0.15 | 0.047 | 0.048 | 0.048 | ||
0 | 0.051 | 0.050 | 0.050 | ||
-0.15 | 0.048 | 0.050 | 0.050 | ||
-0.45 | 0.050 | 0.051 | 0.053 | ||
300 | 0.05 | 0.45 | 0.044 | 0.050 | 0.055 |
0.15 | 0.046 | 0.045 | 0.053 | ||
0 | 0.044 | 0.052 | 0.052 | ||
-0.15 | 0.046 | 0.046 | 0.053 | ||
-0.45 | 0.046 | 0.045 | 0.057 | ||
0.15 | 0.45 | 0.049 | 0.047 | 0.051 | |
0.15 | 0.049 | 0.050 | 0.052 | ||
0 | 0.051 | 0.050 | 0.050 | ||
-0.15 | 0.049 | 0.051 | 0.051 | ||
-0.45 | 0.047 | 0.049 | 0.052 |
—See note to Table 1 for definition of a.