Table 4.
The association signals for the 10 most significant SNPs in bivariate analyses on the empirical GWA data using B_EGEE method
| SNP | Cytoband | Allele | MAFa | pB-valueb | pU-valuec |
|---|---|---|---|---|---|
| rs12613304 | 2p16.1 | A/G | 0.27 | 1.02×10-6 | 1.27×10-6 |
| rs35267016 | 2p16.1 | A/G | 0.14 | 1.44×10-6 | 1.73×10-6 |
| rs12613228 | 2p16.1 | A/G | 0.13 | 1.45×10-6 | 8.04×10-6 |
| rs17049480 | 2p16.1 | A/G | 0.24 | 1.68×10-6 | 1.82×10-6 |
| rs12468708 | 2p16.1 | G/T | 0.42 | 2.21×10-6 | 4.62×10-6 |
| rs887956 | 2p16.1 | A/C | 0.26 | 2.40×10-6 | 1.25×10-5 |
| rs17161597 | 7q21.13 | A/G | 0.07 | 2.75×10-6 | 2.02×10-5 |
| rs12001727 | 9q21.32 | C/T | 0.39 | 3.91×10-6 | 1.29×10-5 |
| rs4660472 | 1p34.2 | A/G | 0.35 | 4.55×10-6 | 7.54×10-6 |
| rs7863577 | 9p13.2 | G/T | 0.10 | 5.58×10-6 | 8.20×10-6 |
a
Note.— MAF, Minor allele frequency
b
pB-value, p-values obtained from B_EGEE
c
pU-value, adjusted p-value for multiple testing for two phenotypes in univariate analyses by Bonferroni correction