Table 2. vps-34 and piki-1 are required for the reduction in cell corpses by mtm-1 RNAi.
| Genotype | No. of cell corpses1 | Changes | p- value2 |
| vps-34(h797);piki-1(ok2346);control RNAi | 16.3±0.9 | ||
| vps-34(h797);piki-1(ok2346);mtm-1 RNAi | 14.7±1.2 | No | 0.3 |
| vps-34(h797)ced-1(e1735);control RNAi | 33.6±0.8 | ||
| vps-34(h797)ced-1(e1735);mtm-1 RNAi | 22.6±1.0 | Reduced | <0.0001 |
| ced-1(e1735);piki-1(ok2346);control RNAi | 36.9±0.5 | ||
| ced-1(e1735);piki-1(ok2346);mtm-1 RNAi | 25.9±1.0 | Reduced | <0.0001 |
| vps-34(h797)ced-1(e1735);piki-1(ok2346);control RNAi | 46.7±0.5 | ||
| vps-34(h797)ced-1(e1735);piki-1(ok2346);mtm-1 RNAi | 47.5±0.8 | No | 0.4 |
| vps-34(h797);ced-6(n2095);control RNAi | 38.4±0.6 | ||
| vps-34(h797)ced-6(n2095);mtm-1 RNAi | 31.6±0.7 | Reduced | <0.0001 |
| ced-6(n2095);piki-1(ok2346);control RNAi | 37.0±0.7 | ||
| ced-6(n2095);piki-1(ok2346);mtm-1 RNAi | 27.3±0.9 | Reduced | <0.0001 |
| vps-34(h797);ced-6(n2095);piki-1(ok2346);control RNAi | 43.5±0.8 | ||
| vps-34(h797);ced-6(n2095);piki-1(ok2346);mtm-1 RNAi | 44.0±0.5 | No | 0.6 |
| vps-34(h797);ced-7(n2094);control RNAi | 32.3±0.5 | ||
| vps-34(h797)ced-7(n2094);mtm-1 RNAi | 23.2±0.8 | Reduced | <0.0001 |
| ced-7(n2094);piki-1(ok2346);control RNAi | 39.1±1.0 | ||
| ced-7(n2094);piki-1(ok2346);mtm-1 RNAi | 32.9±1.6 | Reduced | 0.004 |
| vps-34(h797);ced-7(n2094);piki-1(ok2346);control RNAi | 43.5±0.6 | ||
| vps-34(h797);ced-7(n2094);piki-1(ok2346);mtm-1 RNAi | 46.0±0.7 | increased | 0.009 |
RNAi experiments were performed as described in Materials and Methods. vps-34(h797) mutants were maintained and scored as described in Materials and Methods.
1
Cell corpses were scored in the head region of 4-fold stage embryos as described in Materials and Methods and are shown as mean±s.e.m. At least 15 embryos were scored for each strain.
2
Unpaired t tests were performed to compare control animals with mtm-1 RNAi-treated worms.