. 2009 Aug 28;18(9):1219–1237. doi: 10.1007/s11136-009-9530-y

Table 8.

Relative validity of HRQOL scales by rating of Parkinson’s disease symptoms (N = 96)^a

Scale	Rating of severity of Parkinson’s disease symptoms
Scale	No or mild symptoms (n = 40)	Moderate symptoms (n = 45)	Severe symptoms (n = 11)	F-ratio^b	Relative validity^c
SF-36 v. 1.0 (range: 0–100, where 100 is best quality of life)
Physical Function	77.0^d	47.7^e	30.9^f	20.22	5.04
Role Limitations—Physical	51.3^d	12.2^e	11.4^e	20.23	5.04
Role Limitations—Emotional	90.0^d	68.2^d,e	60.6^e	4.01^c	1.00
Pain	72.8^d	60.4^d	39.6^e	8.38	2.09
Emotional Well-Being	76.5^d	66.8^d,e	57.1^e	6.81	1.70
Energy	56.9^d	42.6^e	29.6^f	9.17	2.29
General Health	60.6^d	49.6^d	34.1^e	7.98	1.99
Social Function	81.9^d	48.6^e	35.2^e	19.95	4.98
SF-36 composite scores (T-scores)
Physical Health (PCS)	42.5^d	32.5^e	26.1^f	21.47	5.35
Mental Health (MCS)	53.1^d	46.9^d,e	42.9^e	4.77	1.19
PDQUALIF (range: 0–100, where 100 is best quality of life)
Social/Role Function	69.5^d	42.5^e	30.6^e	22.55	5.62
Self-Image and Sexuality	75.5^d	52.1^e	36.8^f	24.42	6.09
Sleep	75.0^d	58.0^e	52.5^e	5.30	1.32
Outlook	71.6^d	55.8^d	42.5^e	12.44	3.10
Physical Function	79.4^d	65.0^e	64.0^e	9.56	2.38
Independence	89.4^d	76.1^d	52.5^e	6.00	1.50
Urinary Function	51.3^d	33.6^d,e	17.5^e	5.19	1.29
Total score	73.1^d	54.7^e	42.3^f	24.60	6.13
PDQ-39 (range: 0–100, where 100 is best quality of life)
Mobility	82.4^d	51.6^e	31.9^f	29.22	7.29
Activities of Daily Living	79.3^d	58.7^e	41.3^f	17.27	4.31
Emotional Well-Being	84.7^d	69.9^e	54.2^f	13.01	3.24
Stigma	84.5^d	69.4^d,e	59.7^e	5.21	1.30
Social Support	95.4^d	78.2^e	59.9^f	12.06	3.01
Cognitions	83.3^d	66.9^e	63.6^e	9.71	2.42
Communication	90.1^d	66.9^e	59.1^e	19.02	4.74
Bodily Discomfort	72.3^d	55.6^e	52.3^e	7.93	1.98
Total score	84.0^d	64.7^e	52.7^f	31.29	7.80

^aAll the scales scored on a 0 (worst) to 100 (best) possible range, except for the SF-36 PCS and MCS, which are T-scores (mean = 50, SD = 10) calculated against a reference population

^bOne way between group ANOVAs of HRQOL scale and PD symptom severity

^cReference scale = SF-36 Role Limitations—Emotional (F-ratio = 4.01)

^{d, e, f}Means within a row with different letters differ significantly (P < 0.05; Duncan multiple range)