Table 2.
Time-points of 5-yr overall survival and disease free survival according to each parameter and P-value of univariate survival analysis with log-rank test
| Parameter | 5-yr DFS (%) | 5-yr OS (%) | Log-rank P |
| Overall | 54 | 57.7 | - |
| Sex | 0.77 | ||
| Male | 50.6 | 56.3 | |
| Female | 56.9 | 58.5 | |
| Age (yr) | 0.3 | ||
| < 65 | 55.7 | 59.7 | |
| ≥ 65 | 52.1 | 55.3 | |
| CEA | 0.09 | ||
| < 5 ng/mL | 59.7 | 65.1 | |
| ≥ 5 ng/mL | 48.2 | 50.0 | |
| AJCC staging | < 0.001 | ||
| Stage 1 | 68.6 | 75.0 | |
| Stage 2 | 81.2 | 86.9 | |
| Stage 3 | 39.2 | 41.3 | |
| Stage 4 | 0 | 0 | |
| Tumor size | 0.38 | ||
| T 0-1 | 61.9 | 72.0 | |
| T 2-3 | 52.4 | 55.1 | |
| Nodal status | < 0.001 | ||
| N0 | 73.1 | 79.1 | |
| N1 | 42.6 | 46.1 | |
| N2 | 21 | 21.1 | |
| Metastatic status | < 0.001 | ||
| M0 | 61.1 | 65.2 | |
| M1 | 0 | 0 | |
| Location | 0.03 | ||
| Colon | 61.6 | 65.8 | |
| Rectum | 46.1 | 49.4 | |
| Differentiation | 0.06 | ||
| Well | 61.9 | 62.0 | |
| Moderate | 49.4 | 49.5 | |
| Poor | 34.2 | 34.3 | |
| Staining localization | 0.09 | ||
| Nuclear | 69.2 | 73.3 | |
| Non-nuclear | 50.5 | 54.1 | |
| Staining intensity | 0.61 | ||
| Weak to moderate | 60.9 | 65.4 | |
| Strong to very strong | 50.7 | 54.1 | |
| OSD | < 0.001 | ||
| Low (< 75%) | 34.7 | 63.4 | |
| High (≥ 75%) | 60.5 | 40.0 | |
| NSD | 0.59 | ||
| Low (< 75%) | 51.1 | 55.8 | |
| High (≥ 75%) | 56.5 | 59.3 |
OSD: Overall staining density; NAD: Nuclear staining density; OS: Overall survival; DFS: Disease free survival.