Table 4.
Involvement of salivary and plasma proteomes in KEGG biological pathways
| KEGG pathways | Saliva (entries = 1527) | Plasma (entries = 1415) | Overlap (entries = 368) |
|---|---|---|---|
| Cell communication | 205 | 195 | 85 |
| Carbohydrate metabolism | 160 | 89 | 40 |
| Amino acid metabolism | 164 | 95 | 35 |
| Immune system | 127 | 180 | 44 |
| Signal transduction | 99 | 167 | 20 |
| Lipid metabolism | 67 | 42 | 9 |
| Energy metabolism | 63 | 18 | 11 |
| Translation/transcription | 57 | 17 | 2 |
| Endocrine system | 58 | 62 | 12 |
| Cell motility | 50 | 53 | 18 |
| Nucleotide metabolism | 51 | 34 | 7 |
| Infectious diseases | 52 | 25 | 12 |
| Xenobiotics biodegradation and metabolism | 38 | 33 | 6 |
| Neurodegenerative disorders | 38 | 37 | 16 |
| Others | 52 | 38 | 8 |
| Folding, sorting, and degradation | 27 | 20 | 6 |
| Metabolism of cofactors and vitamins | 28 | 28 | 6 |
| Nervous system | 27 | 28 | 4 |
| Signaling molecules and interaction | 47 | 108 | 16 |
| Cancers | 21 | 25 | 0 |
| Development | 23 | 35 | 1 |
| Glycan biosynthesis and metabolism | 47 | 25 | 5 |
| Cell growth and death | 13 | 40 | 4 |
| Metabolic disorder | 14 | 21 | 1 |
The number of entries represents the total pathways containing saliva proteins, plasma proteins, or the overlapping proteins of saliva and plasma. A protein can be involved in multiple pathways.