Figure 3. Proliferation of OT-1 CD8+ T Cells in Irradiated TAP° Hosts Is Restored by Expression of an Antagonist Peptide.
Donor cells were pooled spleen and lymph node from OT-1 (A) or OT-1 RAG° mice (B). CD8+Vα2+ CFSE-labeled cells (2 × 106) were injected per indicated host. CFSE expression is shown for CD8+Vα2+ cells from spleen on day 5 (A) or day 6 (B) post transfer. Data are representative of at least five experiments.