. 2009 Sep 25;37(22):e145. doi: 10.1093/nar/gkp758

Table 1.

Loading efficiency of siRNA in PK3 or PLGA particles and particle sizes

Submicron particles	PK3–siRNA particle without chloroquine	PK3–siRNA particle with chloroquine (PKCN–siRNA)	PLGA–siRNA particle with chloroquine
Average loading efficiency (%)^a	42.43	59.05	47.95
Particle size (nm)^b	934.2 ± 59.3	887.7 ± 56.7	881.0 ± 514.9

^aThe loading efficiency of Fl-siRNA in the PKCNs was determined by fluorescence of fluorescein (λ_ex/λ_em = 494/518 nm). Loading efficiency (%) = (amount of Fl-siRNA loaded in submicron particle)/(initial amount of Fl-siRNA used to make submicron particle) × 100.

^bParticle size was determined by DLS (mean ± SD).