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. 2009 Nov;1(8-9):371–380. doi: 10.1002/emmm.200900048

Figure 4. Cortical amyloid as detected by PET PIB and its relationship to CSF tau and ptau181 and the ratios of CSF tau/Aβ42 and ptau181/Aβ42 in CDR 0 participants (n = 189).

Figure 4

A linear relationship is observed between the amount of cortical amyloid and

  1. the levels of CSF tau
  2. the levels of CSF ptau181
  3. the ratios of CSF tau/Aβ42 and
  4. the ratios of the ptau181/Aβ42. The correlations between the CSF tau(s)/Aβ42 ratios and MCBP remain significant even when the statistical outlier (high PIB, high ratio) is omitted from the analysis (tau/Aβ42, r = 0.74227, p < 0.0001; ptau181/Aβ42, r = 0.73510, p < 0.0001). All Pearson correlation coefficients are corrected for age.