Table II.
Quantitative Autistic Traits in the first degree relatives of ASD probands. Social Responsiveness Scale Mean scores by gender, categorical “affected” status (on the basis of SRS screening, clinician diagnosis, and/or ADI-R result—see text), and family type (simplex versus multiplex autism), incorporating data from children for whom teacher-report data was available, and for the sub sample of parental pairs (all undiagnosed) assessed by spouse-report. P-values are for two-tailed test, except where indicated.
| Simplex Autism Families |
Multiplex Autism Families |
p Sudent’s t-test |
|
|---|---|---|---|
| Affected Boys (raw teacher-report SRS) |
87.8 (SD=28.3) n=80 |
104.7 (SD=33.8) n=262 |
.0001 |
| Unaffected Boys (raw teacher-report SRS) |
30.7 (SD=23.5) n=89 |
40.3 (SD=28.8) n=29 |
.035* |
| Affected Girls (raw teacher-report SRS) |
97.5 (SD=36.0) n=81 |
||
| Unaffected Girls (raw teacher-report SRS |
23.0 (SD=16.3) n=45 |
||
| Fathers (spouse-report SRS) |
23.8 (SD 17.5) n=41 |
34.3 (SD 23.3) n=58 |
.01 |
| Mothers (spouse-report SRS) |
23.9 (SD 20.1) n=41 |
27.0 (SD 17.8) n=58 |
ns |
*
one-tailed test, see results section