Table 5.

Regions manifesting significant thickness or volume differences between ASD and VC groups.

A) Thickness-based
Regions¹	ASD (mm)	VC (mm)	p-value²
R entorhinal	2.37 ± 0.38	2.87 ± 0.60	0.008**
L entorhinal	2.46 ± 0.50	2.83 ± 0.52	0.04
R lateral orbitofrontal	2.65 ± 0.23	2.91 ± 0.20	0.0006**
L lateral orbitofrontal	2.71 ± 0.25	2.95 ± 0.14	0.0005**
R medial orbitofrontal	2.49 ± 0.29	2.86 ± 0.34	0.001**
L medial orbitofrontal *	2.64 ± 0.21	3.01 ± 0.26	< 0.0001**
R parahippocampal	2.03 ± 0.26	2.24 ± 0.23	0.01
L parahippocampal *	2.08±0.33	2.33 ± 0.34	0.03
R pars triangularis *	2.61 ± 0.15	2.82 ± 0.21	0.002**
L pars triangularis*	2.64 ± 0.19	2.82 ± 0.22	0.01
R temporal pole	2.67 ± 0.53	3.07 ± 0.54	0.03
L temporal pole	2.77 ± 0.61	3.21 ± 0.52	0.02
R rostral middle frontal	2.66 ± 0.15	2.76 ± 0.10	0.03
L caudal anterior cingulated*	3.15 ± 0.41	2.75 ± 0.40	0.004**
L precuneus *	2.74 ± 0.13	2.64 ± 0.15	0.04
L superior parietal	2.63 ± 0.19	2.51 ± 0.15	0.05
L frontal pole *	3.38 ± 0.49	3.73 ± 0.27	0.008**

B) Volume-based
Regions¹	ASD(mm³)	VC(mm³)	p- value²
R entorhinal	1135 ± 345	1496 ± 515	0.02
L entorhinal	1091 ± 476	1471 ± 448	0.02
R medial orbitofrontal	4264 ± 861	5369 ± 1126	0.003
L medial orbitofrontal	4454 ± 859	5319 ± 928	0.006
R lateral orbitofrontal	6771 ± 1623	7881 ± 1316	0.03
R temporal pole	1424 ± 654	1971 ± 651	0.02
L caudal anterior cingulate	1860 ± 558	1388 ± 259	0.001
L parahippocampal	1719 ± 322	1979 ± 385	0.04
L frontal pole	1220 ± 337	1543 ± 421	0.02

Regions marked with “*” were predictor variables chosen by LMT. L: left hemisphere; R: right hemisphere.

Two-sample t-test. P-values marked with “**” were significant at false discovery rate (FDR) q < 0.05 (Benjamini and Hochberg, 1995).

All regions that were found to be significantly different with respect to volume were also found to be significantly different with respect to thickness. L: left hemisphere; R: right hemisphere.

Two-sample t-test. None was chosen using false discovery rate (FDR) q < 0.05 (Benjamini and Hochberg, 1995).