TABLE 4.
Haplotype sharing among LRRK2 2385R carriers
Shared allele frequency |
||||
---|---|---|---|---|
Position (Mb)* | Marker | Allele shared among carriers** | Carriers (n = 46) | Noncarriers (n = 46) |
38989342 | D12S2516 | 254 | 0.79 | 0.50 |
39000026 | rs1896252 | C | 0.77 | 0.49 |
39000101 | rs1427263 | A | 0.78 | 0.51 |
39000140 | rs11176013 | G | 0.77 | 0.49 |
39000168 | rs11564148 | A | 0.66 | 0.32 |
39043595 | G2385R (rs34778348) | – | – | – |
39116867 | D12S2519 | 132 | 0.63 | 0.29 |
39128684 | D12S2521 | 363a | 0.52 | 0.16 |
Map position from the March 2008 human reference genome assembly (NCBI Build 36.3).
Alleles marked in bold were shared among all 2385R carriers.
Two carriers did not share allele 363 at D12S2521 and had the following genotypes: 359, 367 and 367, 375.