Table 1.
Eight Ecological Studies from Europe, America, and Australia (Type A Studies) of Schizophrenia Risk for Subjects In Utero in the First, Second, or Third Trimester of Prenatal Life During the 1957 Pandemic of A2 Influenza
First Author and Publication Year | Region | Na | End of Follow-up Period | Timing of Birth of Control Patients | Relative Risk by Trimester of Exposure | ||
1st | 2nd | 3rd | |||||
Mednick, 1988 | Uusimaa County, Finland | 58 | 1984 | 6 previous y | 0.88 | 0.85 | 0.77 |
Kendell, 1989 | Scotland | 170 | 1988 | 2 previous y | 0.87 | 0.81 | 0.90 |
O’Callaghan, 1991 | Regions of England and Wales | 263 | 1984 | 2 previous and 2 subsequent y | 0.84 | 1.24 | 1.15 |
Torrey, 1991 | 10 U.S. states | 3368 | 1987/1988 | 1 previous and 1 subsequent y | 0.95 | 1.00 | 1.07 |
Erlenmeyer-K, 1994 | Croatia | 82 | 1990 | 2 previous and 2 subsequent y | 0.90 | 0.98 | 1.11 |
Selten, 1994 | The Netherlands | 654 | 1991 | 2 previous and 2 subsequent y | 0.86 | 0.99 | 1.01 |
McGrath, 1994 | Queensland, Australia | 156 | 1988 | 5 previous and 5 subsequent yb | 0.57 | 1.27 | 1.21 |
Morgan, 1997 | Western Australia | 72 | 1996 | 1 previous and 1 subsequent yc | 0.86 | 1.00 | 1.86 |
Number of patients born in period of 9 months after pandemic.
Except 1954, 1957, and 1959.
See Morgan et al18 for details.