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. 2009 Dec 3;36(2):219–228. doi: 10.1093/schbul/sbp147

Table 1.

Eight Ecological Studies from Europe, America, and Australia (Type A Studies) of Schizophrenia Risk for Subjects In Utero in the First, Second, or Third Trimester of Prenatal Life During the 1957 Pandemic of A2 Influenza

First Author and Publication Year Region Na End of Follow-up Period Timing of Birth of Control Patients Relative Risk by Trimester of Exposure
1st 2nd 3rd
Mednick, 1988 Uusimaa County, Finland 58 1984 6 previous y 0.88 0.85 0.77
Kendell, 1989 Scotland 170 1988 2 previous y 0.87 0.81 0.90
O’Callaghan, 1991 Regions of England and Wales 263 1984 2 previous and 2 subsequent y 0.84 1.24 1.15
Torrey, 1991 10 U.S. states 3368 1987/1988 1 previous and 1 subsequent y 0.95 1.00 1.07
Erlenmeyer-K, 1994 Croatia 82 1990 2 previous and 2 subsequent y 0.90 0.98 1.11
Selten, 1994 The Netherlands 654 1991 2 previous and 2 subsequent y 0.86 0.99 1.01
McGrath, 1994 Queensland, Australia 156 1988 5 previous and 5 subsequent yb 0.57 1.27 1.21
Morgan, 1997 Western Australia 72 1996 1 previous and 1 subsequent yc 0.86 1.00 1.86
a

Number of patients born in period of 9 months after pandemic.

b

Except 1954, 1957, and 1959.

c

See Morgan et al18 for details.