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. 2010 Apr 1;6(4):e1000888. doi: 10.1371/journal.pgen.1000888

Figure 3. SNPs with the strongest evidence for association in WTCCC Crohn's disease are more likely to have eQTL function scores >3.

Figure 3

SNPs have been ordered according to their WTCCC Crohn's association p-values from the most to the least significant, and divided in groups of 10,000. For each group bin of 10,000 trait-associated SNPs, the number of SNPs with expression score larger than 3 was calculated and the results are shown in the scatterplot. The horizontal line illustrates the expectation based on the observed eQTL function scores in all SNPs in the WTCCC Crohn's dataset. The dotted lines represent estimated 95% confidence bands obtained using simulations.