Table 2.
Measures of the intraclass correlation coefficients (ICC) for the MZ and DZ groups, Falconer’s heritability estimate (h2), the additive genetic (a2), dominant genetic (d2), shared (c2) and unique environmental (e2) variance components, their confidence interval, the probability p (computed from the structural equation models; these exceed 0.05 when the model fits) and the model that provided the best fit when explaining variance in the volumes of these brain regions across subjects for the scaled data. ROIs: WB- whole brain ; Fr - Frontal lobes ; Par - Parietal lobes ; Temp - Temporal lobes ; Occ - Occipital lobes ; Lmbc - Limbic lobes ; Vent - Ventricles ; BG - Basal Ganglia ; Th - Thalamus
Regions | WB | Fr | Par | Temp | Occ | Lmbc | Vent | BG | Th |
---|---|---|---|---|---|---|---|---|---|
ICCMZ | 0.21 | 0.38 | 0.09 | 0.12 | 0.55 | 0.57 | 0.59 | 0.49 | 0.61 |
ICCDZ | 0.33 | 0.46 | 0.26 | 0.21 | 0.26 | 0.12 | 0 | 0.35 | 0 |
h2 | 0 | 0 | 0 | 0 | 0.58 | 0.91 | 1.17 | 0.27 | 1.21 |
a2(%) | 0 (0 - 25.23) |
0 (0-34.76) |
- - |
14.91 (0-38.41) |
46.84 (1.46 - 65.11) |
17.27 (0.02 - 79.76) |
0 (0-34.92) |
56.97 (0 - 99.93) |
0 (0 - 68.10) |
c2/d2(%) | 27.13 (3.27 - 61.47) |
42.29 (0 - 45.53) |
- - |
0 0 |
7.01 (5.72 - 54.36) |
34.54 (0.01 - 41.67) |
53.12 (9.40 - 53.62) |
0 0 |
58.32 (1.66 - 58.67) |
e2(%) | 73.87 (24.43 - 89.48) |
57.05 (19.70 - 83.03) |
- - |
85.08 (61.58 - 100) |
46.13 (28.53 - 72.13) |
48.18 (28.75 - 73.95) |
46.88 (26.14 - 73.95) |
43.03 (0 - 99.99) |
41.68 (0 - 79.60) |
probability | 0.26 | 0.54 | - | 0.55 | 0.38 | 0.06 | 0.23 | 0.61 | 0.25 |
Best fitting model | ACE | ACE | no fit | AE | ADE | ADE | ADE | AE | ADE |