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hTERT haplotypes and association with exceptional longevity
| Haplotype frequency, % |
|||||||
| Hap | IVS1–187 T > C | 973 G > A (A305A) | 3097 C > T (H1013H) | IVS16+99 C > T | Centenarians (n = 74) | Controls (n = 49) | P value* |
| 1 | T | G | C | C | 34.9 | 53.1 | 0.008 |
| 2 | C | A | C | C | 21.9 | 23.5 | 0.322 |
| 3 | T | G | C | T | 13.7 | 9.2 | 0.007 |
| 4 | C | A | T | C | 10.3 | 5.1 | 0.392 |
| 5 | C | G | C | C | 6.2 | 5.1 | 0.749 |
| 6 | T | G | T | C | 6.8 | 1.0 | 0.024 |
| 7–9 | Others | 6.2 | 3.1 | 0.203 | |||
*Adjusted for age and gender.
