Table 2.
Genes in ADHD CNVs previously associated with neuropsychiatric and neurological disorders
| Gene | Disorder(s)a | Genomic reference(s)b |
|---|---|---|
| A2BP1 | Schizophrenia; autism; mental retardation | (15, 21, 55, 56) |
| APOL4 | Schizophrenia | (57) |
| ATM | Ataxia-telangiectasia; neurodegeneration | (58, 59) |
| AUTS2 | Mental retardation and autism | (60–62) |
| BLMH | Alzheimer's disease | (63) |
| CHL1 | Schizophrenia | (64) |
| CHN2 | Schizophrenia | (65) |
| CNTNAP2 | Schizophrenia; autism; Tourette syndrome | (17, 58, 66–68) |
| CPLX2 | Schizophrenia | (69) |
| CTNND2 | Mental retardation in cri du chat syndrome | (70) |
| DPP6 | Schizophrenia | (21) |
| GRM5 | Schizophrenia; Fragile X syndrome | (71, 72) |
| GRM7 | Schizophrenia | (19) |
| IMMP2L | Autism; Tourette syndrome | (73–76) |
| NKAIN2 | Schizophrenia | (21) |
| PARK2 | Schizophrenia | (21) |
| PDCD10 | Cerebral cavernous malformations | (77) |
| PTPRD | Restless legs syndrome | (33) |
| RTN4 | Schizophrenia | (78) |
| SEPP1 | Schizophrenia | (79) |
| SERPINI1 | Schizophrenia | (80, 81) |
| TACR3 | Schizophrenia | (82) |
Abbreviations: ADHD, attention-deficit/hyperactivity disorder; CNVs, copy number variations.
a
Underlined disorders indicate implication through CNV analysis.
b
References in Table 2 are listed in the Supplementary Materials.