Table 2.
One-Year Changes by Treatment Group
| Variable | Adjusted Mean (SE) |
P Valuea | |
|---|---|---|---|
| Diabetes Support and Education (n=139) | Intensive Lifestyle Intervention (n=125) | ||
| BMI | –0.2 (0.3) | –3.8 (0.3) | <.001 |
| Weight, kg | –0.6 (0.7) | –10.8 (0.7) | <.001 |
| Waist circumference, cm | –0.5 (0.6) | –9.3 (0.7) | <.001 |
| Neck circumference, cm | 0.1 (0.2) | –1.2 (0.2) | <.001 |
| Hemoglobin A1c, % | –0.2 (0.1) | –0.7 (0.1) | <.001 |
| Apnea-hypopnea index | 4.2 (1.4) | –5.4 (1.5) | <.001 |
| Obstructive apnea index | 6.1 (1.4) | –2.5 (1.5) | <.001 |
| Central apnea index | –0.02 (0.2) | 0.02 (0.2) | .85 |
| Hypopnea index | –1.7 (0.7) | –2.9 (0.8) | .28 |
| Oxygen desaturation index, ≥4% | 1.2 (1.3) | –5.5 (1.4) | <.001 |
Abbreviation: BMI, body mass index (calculated as weight in kilograms divided by height in meters squared).
a
P values are for between-group differences based on linear mixed-effects models, with time, treatment, and a time-by-treatment interaction as principal explanatory variables and research site as a fixed effect.