TABLE II.
Study population demographic information
| Repeat group | N | Mean age (SD) |
Race (% White) |
Smoking history (% ever smoked) |
Hormone use (% using hormones) |
Mean BMI (SD) |
Ascertainment (% from GP) |
|---|---|---|---|---|---|---|---|
| All participants | 1001 | 43.3 (15.0)* | 82.4* | 35.9 | 38.4 | 27.0 (6.7) | 32.1* |
| NC (<59 repeats) | 541 | 42.4 (15.9) | 74.9 | 33.3 | 38.9 | 27.0 (7.0) | 57.1 |
| Low PM carriers (59–79 repeats) | 134 | 49.1 (15.3) | 90.1 | 34.3 | 36.4 | 27.6 (5.8) | 9.0 |
| Mid PM carriers (80–100 repeats) | 248 | 43.3 (12.6) | 91.3 | 41.5 | 39.6 | 26.9 (6.7) | 0.0 |
| High PM carriers (101–199 repeats) |
78 | 38.8 (11.7) | 93.3 | 38.5 | 34.2 | 25.8 (6.2) | 0.0 |
Participants were divided into four groups based on FMR1 repeat length. Repeat groups differed significantly with mean age at interview, self-reported race, and ascertainment source (*P <0.0001).
NC, non-carriers; PM, premutation; SD, standard deviation; BMI, body mass index; GP, general population.