Table 4.
Accuracy of Prediction of the R172 IDH2 Mutational Status in Older CN-AML Using Leave-One-Out Cross-Validated Prediction Analysis From Gene- and MicroRNA-Expression Profiles
Classification | Overall Accuracy (%) | Sensitivity (%) | Specificity (%) |
---|---|---|---|
Gene-expression signature | |||
R172 (n = 6) v wild-type (n = 83) | 95.5 | 83.3 | 96.4 |
MicroRNA-expression signature | |||
R172 (n = 6) v wild-type (n = 82) | 93.2 | 83.3 | 93.9 |
Abbreviations: CN, cytogenetically normal; AML, acute myeloid leukemia.