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. Author manuscript; available in PMC: 2010 Sep 21.
Published in final edited form as: Nat Genet. 2009 May 10;41(6):666–676. doi: 10.1038/ng.361

Table 3. Relationship of SNPs at 8 genome-wide significant loci to both blood pressure traits.

For each of eight SNPs, the upper row shows association statistics for the blood pressure trait used for the analysis in which they were selected (SBP or DBP). The lower row (in bold) shows the equivalent association statistics for the alternate blood pressure trait. Results are shown for the 34,433 individuals in the stage 1 Global BPgen GWAS samples.

SNP ID Chr Position (NCBI35) Coded allele Noncoded allele Coded allele frequency N (effective) Trait Beta mm Hg SE P
rs17367504 1 11,797,044 G A 0.14 34,158 SBP −0.79 0.18 1×10−5
DBP 0.50 0.12 3×10−5

rs11191548 10 104,836,168 T C 0.91 33,123 SBP 1.17 0.22 3×10−7
DBP 0.56 0.15 2×10−4

rs12946454 17 40,563,647 T A 0.28 32,120 SBP 0.68 0.15 4×10−6
DBP 0.34 0.09 6×10−4

rs16998073 4 81,541,520 T A 0.21 26,106 DBP 0.65 0.11 7×10−9
SBP 0.74 0.17 1×10−5

rs1530440 10 63,194,597 T C 0.19 32,718 DBP −0.51 0.11 3×10−6
SBP 0.43 0.16 7×10−3

rs653178 12 110,470,476 T C 0.53 30,853 DBP −0.46 0.09 1×10−7
SBP 0.47 0.13 3×10−4

rs1378942 15 72,864,420 C A 0.36 34,126 DBP 0.48 0.09 6×10−8
SBP 0.62 0.13 2×10−6

rs16948048 17 44,795,465 G A 0.39 34,052 DBP 0.40 0.09 5×10−6
SBP 0.41 0.13 2×10−3