Table 3.
Biochemical measures. ATPD causes a significant decrease in the tyrosine/phenylalanine to large neutral amino acids ratio (TYR + PHE:∑LNAAs) in both males and females (standard error of the mean, SEM)
| Absolute values (nmol/ml) | ||||
|---|---|---|---|---|
| T1 | T2 | |||
| Try | Phe | Try | Phe | |
| BAL | ||||
| Male | 48.63 (7.43) | 69.38 (6.02) | 68.66 (10.00) | 179.38 (26.91) |
| Female | 42.47 (4.92) | 78.42 (5.29) | 58.16 (4.24) | 178.34 (16.52) |
| ATPD | ||||
| Male | 47.39 (5.03) | 81.57 (5.92) | 25.63 (1.89) | 39.41 (4.56) |
| Female | 48.16 (4.31) | 86.29 (6.51) | 30.50 (3.36) | 40.15 (3.66) |
T1 baseline measurement taken following fasting and prior to drink administration. T2 4.5 h following drink administration, directly prior to neuropsychological testing began. BAL amino acid balanced drink (placebo condition). ATPD drink lacking in tyrosine or phenylalanine to produce the acute tyrosine/phenylalanine depletion low DA synthesis condition