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. Author manuscript; available in PMC: 2010 Jul 19.
Published in final edited form as: Invest Ophthalmol Vis Sci. 2009 Jul 15;50(12):5630–5638. doi: 10.1167/iovs.09-3791

TABLE 2.

SP Genes Expressed in the Pig Limbal Epithelium

A. SP Overexpressed Genes and Correlation with nSP/SP SI Ratios for Pig and Human Conjunctival Epithelia
Affy ID Symbol R Gene Name/Annotation R-pCNJ R-hCNJ
1 Ssc.7176.1.A1_at CXCR4 14.01 Chemokine (C-X-C motif) receptor 4 24.31 14.51
2 Ssc.22100.1.S1_at SH3BGRL3 12.70 SH3-binding domain glutamic acid-rich protein A 1.09*
3 Ssc.3901.1.A1_at MXD1 9.02 Max dimerization protein 1 9.53 4.07
4 Ssc.18918.1.A1_at GPX2 8.74 Glutathione peroxidase 2 4.96 2.17
5 Ssc.3549.1.S1_at EPAS1 7.55 Endothelial PAS domain protein 1 2.37 0.53*
6 Ssc.1013.1.A1_at MGST1 6.69 Microsomal glutathione S-transferase 1 3.51 1.88
7 Ssc.8261.1.A1_at CYP2C19 6.42 Cytochrome P450 1.17* 2.04
8 Ssc.24193.1.S1_at GRTP1 6.10 Growth hormone regulated TBC protein 1 3.55 4.22
9 Ssc.9522.1.A1_at RNF144B 5.96 Ring finger protein 144b 2.04 A
10 Ssc.10618.1.A1_at NET1 5.72 Neuroepithelial cell trans gene 1 0.97* 1.74*
11 Ssc.23022.1.S1_at RHCG 5.70 Rhesus type C glycoprotein 5.07 2.04
12 Ssc.5978.3.S1_a_at RHBDD2 5.54 Rhomboid, veinlet-like 7 isoform 1 3.27 1.31*
13 Ssc.6738.1.S1_at LNX1 5.54 Ligand of numb-protein X 1 2.62 8.43
14 Ssc.29575.1.A1_at VNN2 5.44 Vanin 2 isoform 1 2.82 5.42
15 Ssc.28055.1.A1_at ZAR1 5.36 Zygote arrest 1-like protein A A
16 Ssc.773.2.S1_at HIST1H2BD 5.34 Histone cluster 1, h2bd 3.74 4.42
17 Ssc.3832.1.S1_at AQP3 5.01 Aquaporin 3 3.35 1.19
18 Ssc.4026.1.S1_at GPN2 4.92 GPN-loop gtpase 2 1.45* NL
19 Ssc.5314.1.S1_at LGALS4 4.83 Lectin, galactoside-binding, 4 (galectin 4) 7.07 0.57*
20 Ssc.7256.1.A1_at RPS20 4.69 Ribosomal protein S20 0.66* 0.81*
22 Ssc.14531.1.S1_at ACADS 4.60 Acyl-Coenzyme A dehydrogen. Short chain 2.19 A
23 Ssc.19335.1.S1_at MYOM1 4.60 Myomesin 1 isoform 2 A 0.52*
24 Ssc.13553.1.A1_at GNA14 4.54 Guanine nucleotide binding protein alpha14 2.72 4.04
25 Ssc.13913.1.S1_at ZMYND8 4.50 Zinc finger, MYND-type containing 8 4.01 NL
26 Ssc.4368.1.S1_at FBXO32 4.49 F-box protein 32 4.53 8.16
27 Ssc.23465.1.S1_at TJP2 4.37 Tight junction protein 2 isoform 1 5.03 0.83*
28 Ssc.19823.1.A1_at ABLIM1 4.37 Actin-binding LIM protein 1 isoform s isoform 4 2.30 1.81
29 Ssc.17990.1.A1_at EEA1 4.34 Early endosome antigen 1 A A
30 Ssc.10025.3.S1_at CEBPD 4.29 CCAAT/enhancer binding protein delta 9.76 1.69*
31 Ssc.8594.1.A1_at BLNK 4.28 B-cell linker isoform 1 2.89 2.47
32 Ssc.28513.1.S1_at NRARP 4.23 NOTCH-regulated ankyrin repeat protein 2.29 NL
33 Ssc.3198.1.S1_at CGN 4.21 Cingulin 2.57 3.60
34 Ssc.17970.1.A1_at TMM54 4.13 Transmembrane protein 54 3.72 NL
35 Ssc.10931.1.S1_at CRYAB 4.10 Crystallin, alpha B 2.40 2.13
36 Ssc.13069.1.A1_at MPN 4.06 Marapsin 2.89 NL
37 Ssc.3476.1.A1_at PIR 4.04 Pirin 3.17 2.08
38 Ssc.114.1.S1_at HSP70 3.99 Heat shock protein 70 4.97 NL
39 Ssc.8871.2.A1_at CDKN1C 3.98 Cyclin-dependent kinase inhib. 1C (p57/kip2) 1.66* 2.43
40 Ssc.779.1.S1_at ELF3 3.86 E74-like factor 3 5.63 7.47
B. SP Underexpressed Genes
Affy ID Symbol R Gene Name/Annotation
1 Ssc.28492.1.S1_at DNAJC2 0.22 Zuotin related factor 1
2 Ssc.30861.1.A1_at FLRT3 0.22 Fibronectin leucine rich transmembrane
3 Ssc.28424.1.A1_at RRP15 0.22 Ribosomal Rna processing 15 homolog
4 Ssc.16209.1.S1_at TNC 0.23 Tenascin c
5 Ssc.8555.1.A1_at INHBA 0.24 Inhibin a
6 Ssc.12822.1.A1_at IL24 0.25 Interleukin 24
7 Ssc.6093.2.A1_at MAP1B 0.26 Microtubule-associated protein 1b
8 Ssc.6662.1.S1_at SEMA6D 0.27 Semaphorin 6d
9 Ssc.7528.1.A1_at MBNL3 0.27 Muscleblind-like 3 isoform g
10 Ssc.16743.1.S1_at FN1 0.27 Fibronectin
11 Ssc.12695.1.S1_at ACSL4 0.28 Acyl-coa synthetase long-chain family member
12 Ssc.29550.1.A1_at ZNF239 0.29 Zinc finger protein 239
13 Ssc.27410.1.S1_at MYCN 0.29 V-myc myelocytomatosis viral related
14 Ssc.15629.1.S1_at WDR3 0.29 Wd repeat-containing protein 3
15 Ssc.24731.1.A1_at MEX3B 0.29 Mex-3 homolog b
16 Ssc.19744.1.S1_at NNP73 0.30 Nucleolar protein 73
17 Ssc.29120.1.A1_at AHCTF1 0.30 At hook containing transcription factor 1
18 Ssc.30843.1.A1_at ADAMDEC 0.30 Disintegrin and metalloproteinase domain-like
19 Ssc.14318.2.A1_at BBS7 0.30 Bardel-biedl syndrome 7
20 Ssc.24741.2.S1_at DNTTIP2 0.30 Deoxynucleotidyltransferase, interacting
21 Ssc.4814.1.A1_at PAN2 0.30 Poly(a) specific ribonuclease subunit homolog
22 Ssc.10709.1.A1_at CNBP 0.31 Zinc finger protein 2 isoform 2
23 Ssc.7062.1.A1_at ASNSD1 0.31 Asparagine synthetase domain containing 1
24 Ssc.19236.1.S1_at SPRED1 0.31 Sprouty-related, evh1 domain containing 1
25 Ssc.31124.1.S1_at COL14A1 0.31 Collagen, type xiv, alpha 1
26 Ssc.30737.1.A1_s_a PNPT1 0.32 Polyribonucleotide nucleotidyltransferase 1
27 Ssc.6670.1.A1_at SLC39A6 0.32 Solute carrier family 39 (zinc transporter)
28 Ssc.30853.1.S1_at FGF2 0.32 Fibroblasr growth factor 2
28 Ssc.25265.1.S1_a_ PRP22 0.32 Death (asp-glu-ala-his) box polypeptide 29
29 Ssc.4597.1.A1_at MASP2 0.32 Mannan-binding lectin serine peptidase 2
30 Ssc.27518.1.A1_at PVRL3 0.32 Poliovirus receptor-related 3
31 Ssc.22032.1.A1_at LARP4 0.32 La ribonucleoprotein domain family, member 4
32 Ssc.17313.2.S1_at CALD1 0.32 Caldesmon 1 isoform 5
33 Ssc.27693.1.A1_a_ ADCY3 0.32 Adenylate cyclase 3
34 Ssc.19406.1.S1_at RBM34 0.32 Rna binding motif protein 34
35 Ssc.2227.1.S1_at GLT25D1 0.33 Glycosyltransferase 25 domain containing 1
36 Ssc.13548.1.S1_at NMD3 0.33 Nmd3 homolog
37 Ssc.21447.1.S1_at EPRS 0.33 Glutamyl-prolyl-trna synthetase
39 Ssc.29187.1.A1_at GJA1 0.33 Gap junction protein, alpha 1
40 Ssc.24285.1.S1_at RPP40 0.33 Ribonuclease P 40kda subunit, isoform 1

NL, not listed n the array; A, absent.

*

Does not comply with the definition for overexpression.